Microscopic Agglutination Test Mat

The centers for disease control and prevention cdc laboratory in atlanta georgia performs.

Microscopic agglutination test mat.

The microscopic agglutination test mat is the reference test method for the serodiagnosis of leptospirosis both in humans and in animals world health organization who 2003. The mat is best used as a screening test when investigating the possibility of l. Microscopic agglutination test mat the mat was performed at the laboratory of infectious diseases of ufu and a cutoff dilution of 1 25 was established which was previously used on crocodilians. 1965 and modified by cole et al.

In 1926 schuffner and mochtar described the phenomenon of agglutination and lysis with human and animal sera and made their dilution series with drops from one and the same pipette. The reaction was read after 16 20 hours. World organisation for animal health oie 2008. Antileptospire antibodies in these samples are detected using the microscopic agglutination test mat.

Microscopic agglutination test mat the mat which was originally described by galton et al. Determination of antibody titer by microscopic agglutination test mat has been used as a tool for leptospirosis diagnosis. It uses panels of live leptospires ideally recent isolates representing the circulating serovars from the area where the patient became infected. Four fold or greater rise in antibody titers between acute and convalescent sera suggests recent leptospira infection.

The microscopic agglutination test mat is the gold standard for sero diagnosis of leptospirosis because of its unsurpassed diagnostic specificity. The microscopic agglutination test mat is the basis of serological diagnosis and classification.